The 2026 ESHRE Annual Meeting, the 42nd European Society of Human Reproduction and Embryology conference, will be held at ExCeL London from July 5–8. This global event focuses on reproductive science and medicine, aiming to promote scientific excellence and best clinical practices in infertility care. It encourages collaboration and the sharing of new research among clinicians, researchers, and professionals. The program covers a wide range of topics, including assisted reproductive technologies (ART), reproductive genetics, management of male and female infertility, advances in embryology and cryopreservation, ethical and legal issues in reproductive health, and the integration of innovative technologies like AI into clinical practice.